And when these giants can't grow by increasing revenue or efficiency, they will look else where to satisfy their investors need for growth. Are GSK and AstraZeneca on the menu?

Unfortunately, synergies based on scale efficiencies usually turn out to be figments of buyers' imaginations.

What do you get with an acquisition of GSK and AZ? No more tax loopholes. Dont see strong pipelines, see lots of buildings/locations, people - not much drug revenue and cash burn of billions/quarter. What do you see with an acquisition of those companies? Precision Medicine Initiative - any of these three companies support President's initiative?

https://uk.finance.yahoo.com/news/pfizer-inc-astrazeneca-plc-glaxosmithkline-104830553.html